Protein Alignment Dfd and MSX1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 72/305 - (23%)
• Similarity: 103/305 - (33%)
• Gaps: 111/305 - (36%)

  Fly   215 GGGYGTANGSVGST------HSQGHSPHSQMMDLP-----LQCSSTEPPTNTALGLQELGLKLEK 268
            |||.|.|..:..:|      ..:|..|......||     |.....:|      |.:|..|...:
Human    26 GGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKP------GAKESALAPSE 84

  Fly   269 RIEEAVPAGQQLQELGM---RLRCDDMGSENDDMSE----------EDRLMLDRSPDELGSNDND 320
            .::   .||...|.||:   .|...|..|....:..          ||.|:...||::
Human    85 GVQ---AAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEK------- 139

  Fly   321 DDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEP------------------- 366
                         .|.|       |||:            .|...|
Human   140 -------------PERT-------PWMQ------------SPRFSPPPARRLSPPACTLRKHKTN 172

  Fly   367 KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKK--DNKLPN 429
            ::.||.:|..|:|.||::|...:||:...|.|.:.:|.|:|.|:||||||||.|.|:  :.:|..
Human   173 RKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEK 237

  Fly   430 TKNVRKKTVDAN--------GNPTPV----------AKKPTKRAA 456
            .|...|..:...        |.|..|          |..|.:|||
Human   238 LKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAA 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	25/51 (49%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		12/56 (21%)
		PTZ00449	<105..>248	CDD:185628	43/181 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		9/79 (11%)
		Homeobox	175..229	CDD:395001	25/53 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910