Protein Alignment Dfd and MEOX2

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_005915.2
• Gene: MEOX2 / 4223
• HGNCID: 7014
• Length: 304
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 99/437 - (22%)
• Similarity: 142/437 - (32%)
• Gaps: 202/437 - (46%)

  Fly    15 VQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHS 79
            ::||.:...||.| |...:...|..:.|.|....:...|..:                :.|:|:.
Human     9 LRSPHATAQGLHP-FSQSSLALHGRSDHMSYPELSTSSSSCI----------------IAGYPNE 56

  Fly    80 MHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHP 144
                  ...:.:.||..|.|.|.|.|   |||       |.|.......:|:
Human    57 ------EGMFASQHHRGHHHHHHHHH---HHH-------HQQQQHQALQTNW------------- 92

  Fly   145 HAHPHQSLGYYVHHAPEFIS--AGAVHS---DPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVG 204
                         |.|:..|  :.|.||   .|.:| ||.
Human    93 -------------HLPQMSSPPSAARHSLCLQPDSG-GPP------------------------- 118

  Fly   205 GSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKR 269
                                     ..|.||       |:.||:     :::||
Human   119 -------------------------ELGSSP-------PVLCSN-----SSSLG----------- 135

  Fly   270 IEEAVPAGQQLQELGMRLRC--DDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDL 332
              .:.|.|         ..|  .|.|.:....:|.::    ||    |.....|   .|||.|
Human   136 --SSTPTG---------AACAPGDYGRQALSPAEAEK----RS----GGKRKSD---SSDSQE-- 176

  Fly   333 MAETTDGERIIYPWMKKIHVAGVANGSY--QPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRR 395
                                     |:|  :...:|:::|||:|:.||.|||.||.::.||||.|
Human   177 -------------------------GNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLR 216

  Fly   396 RIEIAHTLVLSERQIKIWFQNRRMKWK-----------KDNKLPNTK 431
            |.|||..|.|:|||:|:||||||||||           ::.:|.|.|
Human   217 RYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVK 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	34/51 (67%)
MEOX2	NP_005915.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..192		48/287 (17%)
		COG5576	160..284	CDD:227863	50/142 (35%)
		Homeobox	191..243	CDD:278475	34/51 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810