Protein Alignment Dfd and Lmx1a

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 137/659 - (20%)
• Similarity: 213/659 - (32%)
• Gaps: 208/659 - (31%)

  Fly    44 SMTASTG---HMSGAVGGGAGVGSVGGGGA----GGMTGHPHSMHPADMVSDYMAHHHNPH-SHS 100
            |||||:|   |:|.:  ......|:.|..:    ..:||. |..|..........|.|..| .|.
  Fly    38 SMTASSGNSLHLSNS--NNNLPTSISGNNSPTATASLTGQ-HQQHQQQQHQQQQQHPHQQHQQHQ 99

  Fly   101 HSHT----------------HS-LPHHHSNSAISGHHQASAGGYSSN---------------YAN 133
            ..|.                || |....|||..:.::..:.||.|||               .|:
  Fly   100 QQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAAS 164

  Fly   134 ATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVL 198
            |...:.|.....:.....||..|..|....:|.|..:......||||.....:||.|.|.
  Fly   165 AAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGN----- 224

  Fly   199 GGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELG 263
            |.|  .|:.||...|.|||..||:.:..|             .|...||          |..|:|
  Fly   225 GNG--NGNGNGNGNGNGGGAATASAAAAS-------------KLSADCS----------GRTEVG 264

  Fly   264 -LKLEKRIEEAVPAGQQLQE--------------------LGMRLR--CDDMGSENDDMSEEDRL 305
             :|.||..|.....||::.:                    .||:|.  |....|:.....:.|||
  Fly   265 HIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRL 329

  Fly   306 M----------------------------------LDRSPDELGS-------------NDNDDDL 323
            .                                  ..|.|.:.|.             :|.:.::
  Fly   330 FGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEM 394

  Fly   324 ----------GDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQI 378
                      |....||:.:....||.|                       .|||.||..|..|.
  Fly   395 FLAAAAAQHCGFVGLDEEDLLRPRDGRR-----------------------GPKRPRTILTSQQR 436

  Fly   379 LELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGN 443
            .:.:..|..:....|:.|..:|....||.|.:::||||:|.|.||..:       :.|....:|.
  Fly   437 KQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQR-------KAKQNGGSGG 494

  Fly   444 PTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAA 508
            .:...:.....:|:..:....::.:..:|:          :..||...:|.:.|:..:.|..|..
  Fly   495 GSGSGRGTGNSSATDDKDTNDKEDKCVKQE----------LGGDSSGYLGGLDSTFASQPLNPNL 549

  Fly   509 PETTSSYPGSQQHLSNNNN---------NGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQ 564
            |.:...||      :|:|:         :||..:..:::.::.:|||....:.....|.|.|...
  Fly   550 PFSPDDYP------ANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHS 608

  Fly   565 QQSDLMTNL 573
            ...|::.||
  Fly   609 NPHDMLANL 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	17/51 (33%)
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	7/51 (14%)
		LIM	333..388	CDD:295319	3/54 (6%)
		Homeobox	427..480	CDD:278475	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000