Protein Alignment Dfd and NANOGP8

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001342210.1
• Gene: NANOGP8 / 388112
• HGNCID: 23106
• Length: 305
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 59/306 - (19%)
• Similarity: 100/306 - (32%)
• Gaps: 122/306 - (39%)

  Fly   229 HSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMG 293
            |::..||....|||.:|.|   |.::|:                  |.|:|           ...
Human    47 HTETVSPLPSSMDLLIQDS---PDSSTS------------------PKGKQ-----------PTS 79

  Fly   294 SENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANG 358
            :||....:||::.:.:
Human    80 AENSVAKKEDKVPVKK------------------------------------------------- 95

  Fly   359 SYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMK--- 420
                    ::.||.::..|:..|...|...:||:.::..|:::.|.||.:|:|.||||:|||
Human    96 --------QKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKR 152

  Fly   421 WKKDNKLPNTKNVRKKT-----------------VDANGNPTPVAKKPTKRAASKKQQQAQQQQQ 468
            |:|:|...|:..|.:|.                 |:..|| .|:....|...::...|....|..
Human   153 WQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGN-LPMWSNQTWNNSTWSNQTQNIQSW 216

  Fly   469 SQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSS 514
            |......||    .|.:|        .::...|.|:.....|:..|
Human   217 SNHSWNTQT----WCTQS--------WNNQAWNSPFYNCGEESLQS 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	20/54 (37%)
NANOGP8	NP_001342210.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96		17/137 (12%)
		HOX	95..151	CDD:197696	20/112 (18%)
		8 X repeats starting with a Trp in each unit	196..240		9/55 (16%)
		Sufficient for transactivation activity. /evidence=ECO:0000250	196..240		9/55 (16%)
		Sufficient for strong transactivation activity. /evidence=ECO:0000250	241..305		2/10 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910