DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and ap

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_724428.1	Gene:	ap / 35509	FlyBaseID:	FBgn0267978	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	44/208 - (21%)
Similarity:	78/208 - (37%)	Gaps:	59/208 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 TANGSVGSTH---SQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQ 281
            ||:.|:.:|:   :|..|||:         .|:.|.::.:..:...|:        .|||...:.
  Fly   272 TASSSMSATYPYSAQFGSPHN---------DSSSPHSDPSRSIVPTGI--------FVPASHVIN 319

  Fly   282 ELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPW 346
            .|....|            ::.| ...|.|         .|:....::.||..|..|..|
  Fly   320 GLPQPAR------------QKGR-PRKRKP---------KDIEAFTANIDLNTEYVDFGR----- 357

  Fly   347 MKKIHVAGVANGSY-QPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQI 410
                       ||: ......||.||::..||:..::..|..|.....:...:::....|.:|.:
  Fly   358 -----------GSHLSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVL 411

  Fly   411 KIWFQNRRMKWKK 423
            ::||||.|.||::
  Fly   412 QVWFQNARAKWRR 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	14/51 (27%)
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755
		LIM2_Lhx2_Lhx9	206..264	CDD:188763
		Homeobox	371..424	CDD:395001	15/52 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000