DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hlx1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_009293289.1	Gene:	hlx1 / 327096	ZFINID:	ZDB-GENE-030131-5304	Length:	357	Species:	Danio rerio

Alignment Length:	445	Identity:	92/445 - (20%)
Similarity:	145/445 - (32%)	Gaps:	169/445 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 YSSNYANATPPSHPHSHPHAHPHQSLGYYVH--HAPEFISAGAVHSDPTNGYGPAANVPNTSNGG 189
            |:||::..|            .:.|.|:.|.  ..|.|..|..:|      .|.|.|:.
Zfish    10 YASNFSLWT------------AYCSAGFAVDSMKKPSFCIADILH------VGDAENIQ------ 50

  Fly   190 GGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTN 254
               ||.:::  ..:|..|                   ..||.|.         ||:.|...|...
Zfish    51 ---GSSSLM--AHIGARA-------------------QVHSSGS---------PLRPSPVTPDAR 82

  Fly   255 TALGLQELGLKLEKR--IEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSN 317
            ........|:.|..|  |....|..:.| :.|:                 ||::         |.
Zfish    83 LHPAYLRHGIHLTSRAAINAPPPTSKDL-KFGI-----------------DRIL---------ST 120

  Fly   318 DNDDDLGDSDSDEDLMAETTDGERIIYP-WMKKIHVA--------------------GVANGSYQ 361
            |.:....:|.|..||.:       |:.| ....:||:                    .:.|.:.|
Zfish   121 DFEPKSKESPSLRDLTS-------IVSPNRQSAVHVSASPYFASIDPTMSETSSLMGSIGNAARQ 178

  Fly   362 PGMEP----------------------KRQRT----AYTRHQILELEKEFHYNRYLTRRRRIEIA 400
            .|...                      ||:|:    .::..|...|||.|...:|:|:..|.::|
Zfish   179 SGQHQFQDTFPGRPYAVLSKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLA 243

  Fly   401 HTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQ 465
            ..|.|::.|:|:|||||||||:...:....|:..|             ::|.|.||.      .:
Zfish   244 AMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKEK-------------EQPDKSAAE------TE 289

  Fly   466 QQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGN------PPYIPAAPETTSS 514
            |::....:.:..|..:|.  .|..|...||..|..|      |..:|.:.:.|||
Zfish   290 QKERDDSECETEPSESEF--EDGPEDKSDVDISDLNKASVIIPGPLPVSTQDTSS 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	22/55 (40%)
hlx1	XP_009293289.1	Homeobox	212..265	CDD:278475	21/52 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910