Protein Alignment Dfd and HOXD11

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 92/367 - (25%)
• Similarity: 126/367 - (34%)
• Gaps: 126/367 - (34%)

  Fly   127 YSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYG-PAANVPNTSNGGG 190
            ||||.|           ||..|.:.:.:                   ..|| ..|..|  ..|||
Human    47 YSSNLA-----------PHVQPVREVAF-------------------RDYGLERAKWP--YRGGG 79

  Fly   191 GGGSGAVLGGGAVGGSANGYYGGYGG--GYGTANGSVGSTHSQGHSPHSQMMDLPLQ-------- 245
            ||||.   |||:.||...|..||.||  .|..|..:..:..:.......|...||..
Human    80 GGGSA---GGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLF 141

  Fly   246 ------CSSTEPPTN---------TALGLQELGLKLEKRIEEAVP----AGQQLQELGMRLRCDD 291
                  |::..||..         :|:|...:..:...:..||.|    ||.|...
Human   142 KAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPP--------- 197

  Fly   292 MGSENDDMSEEDRLMLDRSPDELGSNDNDDD-LGDSDSDEDLMAETTDGERIIYPWMKKIHVAGV 355
                           ....|...|:.|..|. .|..........:.|.|.          ...|.
Human   198 ---------------PPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGS----------EPKGA 237

  Fly   356 ANGSYQPGMEP------------------KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHT 402
            |.||...|..|                  :::|..||::||.|||:||.:|.|:.:.:|::::..
Human   238 AEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRM 302

  Fly   403 LVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNP 444
            |.|::||:||||||||||.||.|        |.:.....|||
Human   303 LNLTDRQVKIWFQNRRMKEKKLN--------RDRLQYFTGNP 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	27/51 (53%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:288866	40/172 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		19/124 (15%)
		Homeobox	269..322	CDD:278475	27/52 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910