Protein Alignment Dfd and HOXD8

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 98/370 - (26%)
• Similarity: 138/370 - (37%)
• Gaps: 128/370 - (34%)

  Fly   111 HSNSAISGHHQASAGGYSSNYANATPPSHPHSHP--HAHPHQSLGYYVHHAPEFISAGAVHSDPT 173
            |....:.|.|.|:|..... |.|:. ...||:.|  |||||.|
Human    35 HFAPEVGGRHAAAAAALQL-YGNSA-AGFPHAPPQAHAHPHPS---------------------- 75

  Fly   174 NGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQG--HSPH 236
                     |..|..|.||..|.        |....:.||         ||..:.:...  ..||
Human    76 ---------PPPSGTGCGGREGR--------GQEYFHPGG---------GSPAAAYQAAPPPPPH 114

  Fly   237 SQMMDLPLQCSST----EPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSEND 297
            ......|..|...    ||.  ...|...|.       .:.:...||..||   ::..|..|.:.
Human   115 PPPPPPPPPCGGIACHGEPA--KFYGYDNLQ-------RQPIFTTQQEAEL---VQYPDCKSSSG 167

  Fly   298 DMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQP 362
            ::.|:        ||.|..:.:...:                    :|||:             |
Human   168 NIGED--------PDHLNQSSSPSQM--------------------FPWMR-------------P 191

  Fly   363 GMEP--KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDN 425
            ...|  :|.|..|:|.|.|||||||.:|.||||:||||::|.|.|:|||:|||||||||||||:|
Human   192 QAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKEN 256

  Fly   426 KLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQ 470
                           |.:..||:::..|...:||:.|..::.:::
Human   257 ---------------NKDKFPVSRQEVKDGETKKEAQELEEDRAE 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	36/51 (71%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		24/114 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		11/79 (14%)
		Homeobox	201..253	CDD:278475	36/51 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		8/47 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4642
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860