Protein Alignment Dfd and HOXD4

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 105/303 - (34%)
• Similarity: 127/303 - (41%)
• Gaps: 100/303 - (33%)

  Fly   153 GYYVHHAPEFISAGAVHSD--PTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYG 215
            ||......::...||..:|  |...| |..:......||.|.|.|:.|.....|...    ||.|
Human    27 GYLGEQGADYYGGGAQGADFQPPGLY-PRPDFGEQPFGGSGPGPGSALPARGHGQEP----GGPG 86

  Fly   216 GGYGTANGSVGSTHSQGHSPHSQMMDLP-----LQCSSTEPPTNTALGLQELGLKLEKRIEEAVP 275
            |.|........:..:...:|      ||     .|....:||:.|||
Human    87 GHYAAPGEPCPAPPAPPPAP------LPGARAYSQSDPKQPPSGTAL------------------ 127

  Fly   276 AGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGE 340
                                             :.|
Human   128 ---------------------------------KQP----------------------------- 130

  Fly   341 RIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVL 405
            .::||||||:||..| |.:|..| ||||.||||||.|:||||||||:||||||||||||||||.|
Human   131 AVVYPWMKKVHVNSV-NPNYTGG-EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCL 193

  Fly   406 SERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVA 448
            |||||||||||||||||||:||||||.....:..::...:.||
Human   194 SERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVA 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	47/51 (92%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		25/106 (24%)
		Antp-type hexapeptide	133..138		3/4 (75%)
		Homeobox	157..210	CDD:306543	47/52 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		9/25 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I6194
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		otm40488
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.910