Protein Alignment Dfd and HOXD3

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 115/468 - (24%)
• Similarity: 159/468 - (33%)
• Gaps: 167/468 - (35%)

  Fly   125 GGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGG 189
            |||  .|:..|              .:.||...|.| :....|..|..|:..|.|.::.:::...
Human    30 GGY--GYSKTT--------------DTYGYSTPHQP-YPPPAAASSLDTDYPGSACSIQSSAPLR 77

  Fly   190 GGGGSGAVLGGGAV-GGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPT 253
            .....||.|.|..: .|:.|    ..|||.|:....:.| ..|...|......||     ...||
Human    78 APAHKGAELNGSCMRPGTGN----SQGGGGGSQPPGLNS-EQQPPQPPPPPPTLP-----PSSPT 132

  Fly   254 NTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSND 318
            |...|               |||.:            ..|..|
Human   133 NPGGG---------------VPAKK------------PKGGPN---------------------- 148

  Fly   319 NDDDLGDSDSDEDLMAETTDGERIIYPWMKKIH----------VAGVA-NGSYQPGMEPKRQRTA 372
                  .|.|...:..:       |:||||:..          .||.: .....||...||.|||
Human   149 ------ASSSSATISKQ-------IFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTA 200

  Fly   373 YTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKT 437
            ||..|::|||||||:||||.|.||:|:|:.|.|:||||||||||||||:|||.|       .|..
Human   201 YTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK-------AKGI 258

  Fly   438 VDANGNPTPVAKKPTKRAASKKQQQAQ------------------QQQQSQQQQTQQTPVMNECI 484
            :.:..:.:|....|...||.......|                  :.|.:.......|..::.|:
Human   259 LHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCL 323

  Fly   485 RSDSLESI-------------GDVSSSL-GNPPYI---------PAA-----------PETTS-- 513
            ......:.             |..|::| |:|.|:         ||:           |.:.|
Human   324 PQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVD 388

  Fly   514 -----SYPGSQQH 521
                 ..||:..|
Human   389 YSCAAQIPGNHHH 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	38/51 (75%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		36/200 (18%)
		Antp-type hexapeptide	160..165		3/4 (75%)
		Homeobox	198..250	CDD:306543	38/51 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		6/33 (18%)
		DUF4074	369..430	CDD:315871	6/33 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810