Protein Alignment Dfd and HOXC4

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 127/470 - (27%)
• Similarity: 154/470 - (32%)
• Gaps: 224/470 - (47%)

  Fly     1 MSSFLMGYPHAPHHVQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSV 65
            |||:||.              .|.:||||||..:        ||.
Human     3 MSSYLMD--------------SNYIDPKFPPCEE--------YSQ-------------------- 25

  Fly    66 GGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSN 130
                                 :.|:. .|:|..:..:......|||.
Human    26 ---------------------NSYIP-EHSPEYYGRTRESGFQHHHQ------------------ 50

  Fly   131 YANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSG 195
              ...||..|.                  |.:               |......||..|.|...|
Human    51 --ELYPPPPPR------------------PSY---------------PERQYSCTSLQGPGNSRG 80

  Fly   196 AVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQ 260
                                      :|...:.|.......|.....||..:|..|
Human    81 --------------------------HGPAQAGHHHPEKSQSLCEPAPLSGASASP--------- 110

  Fly   261 ELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGD 325
                      ..|.||..|                             .:||...|
Human   111 ----------SPAPPACSQ-----------------------------PAPDHPSS--------- 127

  Fly   326 SDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRY 390
                      ....:.|:|||||||||:.| |.:|..| ||||.||||||.|:||||||||||||
Human   128 ----------AASKQPIVYPWMKKIHVSTV-NPNYNGG-EPKRSRTAYTRQQVLELEKEFHYNRY 180

  Fly   391 LTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRK--------KTVDANGNPTPV 447
            |||||||||||:|.||||||||||||||||||||::||||| ||.        .|:.|   .||.
Human   181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTK-VRSAPPAGAAPSTLSA---ATPG 241

  Fly   448 AKKPTKRAASKKQQQ 462
            ..:...::|:..:||
Human   242 TSEDHSQSATPPEQQ 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	47/51 (92%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		33/306 (11%)
		Antp-type hexapeptide	135..140		3/4 (75%)
		Homeobox	159..213	CDD:395001	48/53 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		15/47 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I6194
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		otm40488
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4536
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.940