DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dfd and HOXB7

DIOPT Version :9

Sequence 1:NP_477201.1 Gene:Dfd / 40832 FlyBaseID:FBgn0000439 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_004493.3 Gene:HOXB7 / 3217 HGNCID:5118 Length:217 Species:Homo sapiens


Alignment Length:259 Identity:93/259 - (35%)
Similarity:104/259 - (40%) Gaps:104/259 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   184 NTSNGGGGGGSGAVL----------GGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQ 238
            |....|.|.||||..          |||..|.||.|.   |..|||....|..            
Human    37 NPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGV---YAAGYGLEPSSFN------------ 86

  Fly   239 MMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEED 303
                 :.|:..|         |.|         ..|..|...:..|               ::|.
Human    87 -----MHCAPFE---------QNL---------SGVCPGDSAKAAG---------------AKEQ 113

  Fly   304 RLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKR 368
            |                        |.||.||:...   |||||:            ..|.:.||
Human   114 R------------------------DSDLAAESNFR---IYPWMR------------SSGTDRKR 139

  Fly   369 QRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKL--PNT 430
            .|..|||:|.|||||||||||||||||||||||||.|:|||||||||||||||||:||.  |.|
Human   140 GRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGT 203

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DfdNP_477201.1 Homeobox 370..422 CDD:278475 45/51 (88%)
HOXB7NP_004493.3 Antp-type hexapeptide 126..131 4/4 (100%)
Homeobox 141..193 CDD:278475 45/51 (88%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..217 5/10 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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