DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Hoxc5

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001101586.1	Gene:	Hoxc5 / 315341	RGDID:	1307584	Length:	222	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	84/231 - (36%)
Similarity:	109/231 - (47%)	Gaps:	30/231 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 ANGYY------GGYG----GGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQE 261
            ||.:|      ..|.    |.||:|:....|.:..|          .|..|.|.||...:..|..
  Rat     6 ANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYG----------GLDLSITFPPPAPSNSLHG 60

  Fly   262 LGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDS 326
            :.:....|.....||.......|..|..|:....|..|..:.............|.:..::...:
  Rat    61 VDMAANPRAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQT 125

  Fly   327 DSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYL 391
            .....|.......:  |||||.|:|::...:|        ||.||:|||:|.||||||||:||||
  Rat   126 GQPAGLSQPPAPPQ--IYPWMTKLHMSHETDG--------KRSRTSYTRYQTLELEKEFHFNRYL 180

  Fly   392 TRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKL 427
            |||||||||:.|.|:||||||||||||||||||:|:
  Rat   181 TRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKM 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	43/51 (84%)
Hoxc5	NP_001101586.1	COG5373	65..>142	CDD:227665	11/78 (14%)
Hoxc5	NP_001101586.1	Homeobox	158..212	CDD:395001	44/53 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810