Protein Alignment Dfd and MNX1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_005506.3
• Gene: MNX1 / 3110
• HGNCID: 4979
• Length: 401
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 116/510 - (22%)
• Similarity: 167/510 - (32%)
• Gaps: 180/510 - (35%)

  Fly    44 SMTASTGHMSGAVGGGAGVGSVGGGGAGGMTG--HPHSMHPADMVSDYM-AHHHNPHSHSHSHTH 105
            ::..|....:...|||.|    |||.:||.:|  .|.|..|....:|.: |...:|.....:|..
Human    29 ALVTSLAAAASGTGGGGG----GGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCA 89

  Fly   106 SLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHS 170
            .||.       .|...|..||      ..|...|...|.||||
Human    90 LLPK-------PGFLGAGGGG------GGTGGGHGGPHHHAHP---------------------- 119

  Fly   171 DPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYY-GGYGGGYGTANGSVGSTHSQGHS 234
                              |....:.|.....|.||.|.|.: ||..||.|
Human   120 ------------------GAAAAAAAAAAAAAAGGLALGLHPGGAQGGAG--------------- 151

  Fly   235 PHSQMMDLPLQCSSTEPP--------TNTALGLQELGLKLE-KRIEEAVPA--------GQQLQE 282
                   ||.|.:....|        ...||..|...|... .:::.|.||        |....:
Human   152 -------LPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQ 209

  Fly   283 LGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWM 347
            |...||....|           ::|.:.||           .:|.:..:|:.:.
Human   210 LDQWLRASTAG-----------MILPKMPD-----------FNSQAQSNLLGKC----------- 241

  Fly   348 KKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKI 412
                               :|.|||:|..|:||||.:|..|:||:|.:|.|:|.:|:|:|.|:||
Human   242 -------------------RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKI 287

  Fly   413 WFQNRRMKWKKDNKLPN--TKNVRKK----------------TVDANGNPTPVAKKPTKRAASKK 459
            ||||||||||:..|...  .:...|:                ..:..|.|.|..|...:|....:
Human   288 WFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLR 352

  Fly   460 QQQAQQQQQSQQQQTQQTPVMN-ECIRSDSLESIGDVSSSLGNPPYIPA---APE 510
            ....::.:....:  ...|..| ..:.:.|    .|.||...:||..|:   ||:
Human   353 DSDPEEDEDEDDE--DHFPYSNGASVHAAS----SDCSSEDDSPPPRPSHQPAPQ 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	31/51 (61%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..78		15/44 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		9/64 (14%)
		Homeobox	244..297	CDD:278475	31/52 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..401		17/107 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810