Protein Alignment Dfd and nkx2.3

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_571498.1
• Gene: nkx2.3 / 30698
• ZFINID: ZDB-GENE-990415-178
• Length: 321
• Species: Danio rerio
• Alignment Length: 377
• Identity: 89/377 - (23%)
• Similarity: 136/377 - (36%)
• Gaps: 142/377 - (37%)

  Fly   240 MDLPLQCSSTEPPTNTALGLQELGLKLE---KRIEEAVPAGQQLQ---ELGMRLRC--------- 289
            |.||      .|.|:|...:::: ||||   ::::...||....|   ||..|.:.
Zfish     1 MMLP------SPVTSTPFSVKDI-LKLEQQTRQLQSLHPASHHAQLHPELQDRFQAPSSCFLGGG 58

  Fly   290 DDMG-SENDD-------MSEEDRLM-LDRSP-----DELGSNDN--DDDLGDSDSDE-------- 330
            |..| |:|::       :|.:|.|: ...||     ..||..|.  :|:|.|.::..
Zfish    59 DSPGFSDNEEKMSFLNSLSMQDSLVESSLSPPMFVHPALGHVDTKLEDELEDHETKSCGAILRTP 123

  Fly   331 DLMAET-TDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRT------AYTRHQILELEKEFHYN 388
            :..||. :|.||                        .:||||      .:::.|:.|||:.|...
Zfish   124 ECEAEVHSDTER------------------------AQRQRTRRKPRVLFSQAQVFELERRFKQQ 164

  Fly   389 RYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTK 453
            |||:...|..:|.||.|:..|:||||||||.|.|:..        :.||::..|:..|   .|.:
Zfish   165 RYLSAPEREHLASTLKLTSTQVKIWFQNRRYKCKRQR--------QDKTLEMAGHHHP---PPPR 218

  Fly   454 RAASKKQQQAQQQQQSQQQQTQQTPVM----NECIRSDSLESIGDVSSSLGNPPYIPAAPETTSS 514
            |.|                    .||:    ..|:..         |.|......:...|.|.:.
Zfish   219 RVA--------------------VPVLVRDGKPCLTG---------SQSYNTTYAVNPGPYTYNG 254

  Fly   515 YPGSQQHLSNNNNNGSGN--------------NNNNNNNNNSNLNNNNNNNQ 552
            |       |:.||....|              |.:.|...:.:|||....:|
Zfish   255 Y-------SSYNNAAYTNPYSCTYPSLPPLPANTSTNALMSMSLNNLGTYSQ 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	27/61 (44%)
nkx2.3	NP_571498.1	Homeodomain	143..199	CDD:459649	23/55 (42%)