DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hoxb6a

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_571194.1	Gene:	hoxb6a / 30341	ZFINID:	ZDB-GENE-990415-106	Length:	228	Species:	Danio rerio

Alignment Length:	209	Identity:	85/209 - (40%)
Similarity:	106/209 - (50%)	Gaps:	41/209 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLR------CD----DMGSEN 296
            :||..|....|.....|....|..::   |:|.|:....|..|...|      ||    ....|.
Zfish    25 IPLYSSGYTDPLRHYPGAAYGGSSVQ---EKAYPSSFYQQANGAYSRATAAGPCDYATASFYREK 86

  Fly   297 DDMS-----EEDRLMLD---RSPDELGSNDNDDDLGDS---DSDEDLMAETTDGERIIYPWMKKI 350
            |...     ||...:|.   |..|..||.      |.|   ::||...:..      :||||:::
Zfish    87 DPACALASIEEHSFVLSQDHRKTDCTGST------GKSIYPEADEQKPSAP------VYPWMQRM 139

  Fly   351 HVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQ 415
            :   ..||::  |...:|.|..|||:|.||||||||:||||||||||||||.|.|:|||||||||
Zfish   140 N---SCNGTF--GNAGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 199

  Fly   416 NRRMKWKKDNKLPN 429
            ||||||||:|||.|
Zfish   200 NRRMKWKKENKLIN 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	43/51 (84%)
hoxb6a	NP_571194.1	Antp-type hexapeptide	132..137		3/4 (75%)
hoxb6a	NP_571194.1	Homeobox	154..206	CDD:278475	43/51 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810