DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Meox2

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_058845.2	Gene:	Meox2 / 29279	RGDID:	3079	Length:	303	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	100/441 - (22%)
Similarity:	136/441 - (30%)	Gaps:	211/441 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHS 79
            ::||.:...||.| |...:...|..:.|.|....:...|..:                :.|:|:.
  Rat     9 LRSPHATAQGLHP-FSQSSLALHGRSDHMSYPELSTSSSSCI----------------IAGYPNE 56

  Fly    80 MHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHP 144
                  ...:.:.||..|.|.|.|.|   |||...    .|||    ..||:
  Rat    57 ------EGMFASQHHRGHHHHHHHHH---HHHQQQ----QHQA----LQSNW------------- 91

  Fly   145 HAHPHQSLGYYVHHAPEFIS--AGAVHS---------DPTNGYGPAANVPNTSNGGGGGGSGAVL 198
                         |.|:..|  :.|.||         .|..|..|.....|:|:.|....:||
  Rat    92 -------------HLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGA-- 141

  Fly   199 GGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELG 263
                  ..|.|.||                 .|..||
  Rat   142 ------ACAPGDYG-----------------RQALSP---------------------------- 155

  Fly   264 LKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDS 328
            .::|||                                            .||....|   .|||
  Rat   156 AEVEKR--------------------------------------------SGSKRKSD---SSDS 173

  Fly   329 DEDLMAETTDGERIIYPWMKKIHVAGVANGSY--QPGMEPKRQRTAYTRHQILELEKEFHYNRYL 391
            .|                           |:|  :...:|:::|||:|:.||.|||.||.::.||
  Rat   174 QE---------------------------GNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYL 211

  Fly   392 TRRRRIEIAHTLVLSERQIKIWFQNRRMKWK-----------KDNKLPNTK 431
            ||.||.|||..|.|:|||:|:||||||||||           ::.:|.|.|
  Rat   212 TRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVK 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	34/51 (67%)
Meox2	NP_058845.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..191		49/291 (17%)
		Homeobox	190..243	CDD:395001	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900