Protein Alignment Dfd and GBX2

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001476.2
• Gene: GBX2 / 2637
• HGNCID: 4186
• Length: 348
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 96/353 - (27%)
• Similarity: 135/353 - (38%)
• Gaps: 94/353 - (26%)

  Fly   134 ATPPSHPHSHPHAHPHQSLGYYVHHA-------------PEFISAGAVHSDPTNGYGPAAN--VP 183
            |.||:|||   |..|....|:....|             |...||...|.:     ..||.  .|
Human    73 ALPPAHPH---HQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE-----AAAARKFAP 129

  Fly   184 NTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSS 248
            ....|||.......|...|..|.          |:....||:                  |..|:
Human   130 QPLPGGGNFDKAEALQADAEDGK----------GFLAKEGSL------------------LAFSA 166

  Fly   249 TEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSEND-DMSEEDRLMLDRSPD 312
            .|....:.:|......|.|.::|:. |.|::          :....|:| |.|.:|.|....:..
Human   167 AETVQASLVGAVRGQGKDESKVEDD-PKGKE----------ESFSLESDVDYSSDDNLTGQAAHK 220

  Fly   313 ELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQ 377
            |       :|.|.:      :.||...             :|.|..:...| :.:|:|||:|..|
Human   221 E-------EDPGHA------LEETPPS-------------SGAAGSTTSTG-KNRRRRTAFTSEQ 258

  Fly   378 ILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANG 442
            :||||||||..:||:...|.:|||.|.|||.|:||||||||.|||:    ....|...||.:.:.
Human   259 LLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR----VKAGNANSKTGEPSR 319

  Fly   443 NPTPVAKKPTKRAASKKQQQAQQQQQSQ 470
            ||..|...|...:....:.|.||.:|::
Human   320 NPKIVVPIPVHVSRFAIRSQHQQLEQAR 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	33/51 (65%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		6/10 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		9/32 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		20/109 (18%)
		Homeobox	250..303	CDD:306543	33/52 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810