Protein Alignment Dfd and GBX1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 105/438 - (23%)
• Similarity: 153/438 - (34%)
• Gaps: 111/438 - (25%)

  Fly    57 GGGAGVGSVGGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQ 121
            |||:..|..||||.||    |.:....|
Human     5 GGGSAPGGNGGGGGGG----PGTAFSID------------------------------------- 28

  Fly   122 ASAGGYSSNYANATPPSHPH----SHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANV 182
                    :.....||...|    .:|...|::.|......||..:.||.....|...:  |..:
Human    29 --------SLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASF--AGRL 83

  Fly   183 PNTSNGGGGGGSGAVLG-GGAVGGSA---NGYYG------GYGGGYGTA---NGSVGSTHSQGHS 234
            .||...|.|....:::. ..|:...|   :.:||      .......||   |...|....:|..
Human    84 TNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAAAAAAAAATAARNNPEPGGRRPEGGL 148

  Fly   235 PHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDM 299
            ...::  ||.:....|||...           .....|..|:               :.:|....
Human   149 EADEL--LPAREKVAEPPPPP-----------PPHFSETFPS---------------LPAEGKVY 185

  Fly   300 SEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKI---------HVAGV 355
            |.::..:...:.|..||...::..|....|:..:..:..|...:.....|:         ..|.|
Human   186 SSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPV 250

  Fly   356 ANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMK 420
            ..|...||.:.:|:|||:|..|:||||||||..:||:...|.:|||.|.|||.|:||||||||.|
Human   251 TAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAK 315

  Fly   421 WKKDNKLPNTKNVRKKTVDANGNPTPVAKKP--TKRAASKKQQQAQQQ 466
            ||:    ....||..::.:...||..|...|  ..|.|.:.|.|..:|
Human   316 WKR----IKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQ 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	33/51 (65%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		12/74 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		27/164 (16%)
		Homeobox	264..317	CDD:306543	33/52 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810