DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dfd and NKX2-8

DIOPT Version :9

Sequence 1:NP_477201.1 Gene:Dfd / 40832 FlyBaseID:FBgn0000439 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_055175.2 Gene:NKX2-8 / 26257 HGNCID:16364 Length:239 Species:Homo sapiens


Alignment Length:137 Identity:41/137 - (29%)
Similarity:59/137 - (43%) Gaps:22/137 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   298 DMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHV-AGVANGSYQ 361
            |:.|:|...|.|...|           ......|..|...|.||..||...:..: ....:.|.:
Human    16 DLPEQDAQHLPRREPE-----------PRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQR 69

  Fly   362 PGMEP----------KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQN 416
            |...|          |::|..:::.|.||||:.|...|||:...|.::|..|.|:..|:||||||
Human    70 PSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQN 134

  Fly   417 RRMKWKK 423
            .|.|.|:
Human   135 HRYKLKR 141

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DfdNP_477201.1 Homeobox 370..422 CDD:278475 23/51 (45%)
NKX2-8NP_055175.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..87 17/81 (21%)
Homeobox 87..140 CDD:278475 23/52 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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