Protein Alignment Dfd and NKX2-8

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 41/137 - (29%)
• Similarity: 59/137 - (43%)
• Gaps: 22/137 - (16%)

  Fly   298 DMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHV-AGVANGSYQ 361
            |:.|:|...|.|...|           ......|..|...|.||..||...:..: ....:.|.:
Human    16 DLPEQDAQHLPRREPE-----------PRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQR 69

  Fly   362 PGMEP----------KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQN 416
            |...|          |::|..:::.|.||||:.|...|||:...|.::|..|.|:..|:||||||
Human    70 PSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQN 134

  Fly   417 RRMKWKK 423
            .|.|.|:
Human   135 HRYKLKR 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	24/55 (44%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		17/81 (21%)
		Homeodomain	85..141	CDD:459649	24/55 (44%)