DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dfd and unc-42

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001263845.1	Gene:	unc-42 / 192081	WormBaseID:	WBGene00006778	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	54/245 - (22%)
Similarity:	91/245 - (37%)	Gaps:	54/245 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 QQLQELGMRLRCDDM----GSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTD 338
            :::::||:.|.  |.    .|..|.:|...|.:.|.|.|........:.||.|.....:...|..
Worm    20 EKVKDLGVSLH--DFTAYYPSSLDTVSASLRPISDPSSDGAFKKIKTEGLGGSVFGSSIAGVTNT 82

  Fly   339 GERII---YPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIA 400
            ..|:.   .|..::::             ..:|.||.:|:.|:.||:..|..:.|.....|.|:|
Worm    83 PARLCSLERPESERLN-------------SRRRHRTTFTQEQLQELDAAFQKSHYPDIYVREELA 134

  Fly   401 HTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQ 465
            ....|:|.:|::||||||.|.:|..|..|      |.::.   |......|......:....|..
Worm   135 RITKLNEARIQVWFQNRRAKHRKHEKQLN------KAINP---PHSFLSNPANTLMRQGMYPAAL 190

  Fly   466 QQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSY 515
            .:.....|:.|.|:                       ||..|:|..::|:
Worm   191 NRDGFWYQSYQRPM-----------------------PYPTASPSYSNSF 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	21/51 (41%)
unc-42	NP_001263845.1	Homeobox	103..157	CDD:365835	21/53 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910