DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Phox2b

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_032914.1	Gene:	Phox2b / 18935	MGIID:	1100882	Length:	314	Species:	Mus musculus

Alignment Length:	119	Identity:	32/119 - (26%)
Similarity:	56/119 - (47%)	Gaps:	27/119 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 GMEPKRQ----RTAYTRHQILELEKEF---HYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMK 420
            |:..||:    ||.:|..|:.|||:.|   ||....||.   |:|..:.|:|.::::||||||.|
Mouse    91 GLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTRE---ELALKIDLTEARVQVWFQNRRAK 152

  Fly   421 WKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQT 474
            ::|..:                 ....|....|..:|.|:..:.:..:|::.::
Mouse   153 FRKQER-----------------AAAAAAAAAKNGSSGKKSDSSRDDESKEAKS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	23/54 (43%)
Phox2b	NP_032914.1	Homeobox	102..155	CDD:395001	23/55 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..246		5/28 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910