DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Pdx1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_032840.1	Gene:	Pdx1 / 18609	MGIID:	102851	Length:	284	Species:	Mus musculus

Alignment Length:	87	Identity:	52/87 - (59%)
Similarity:	64/87 - (73%)	Gaps:	7/87 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 YPWMK--KIHV--AGVANGSY--QPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHT 402
            :||||  |.|.  ...|.|:|  :| .|.||.||||||.|:|||||||.:|:|::|.||:|:|..
Mouse   120 FPWMKSTKAHAWKGQWAGGAYTAEP-EENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVM 183

  Fly   403 LVLSERQIKIWFQNRRMKWKKD 424
            |.|:||.||||||||||||||:
Mouse   184 LNLTERHIKIWFQNRRMKWKKE 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	36/51 (71%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..116
		Antp-type hexapeptide	119..124		2/3 (67%)
		Homeobox	150..203	CDD:278475	36/52 (69%)
		Nuclear localization signal	198..204		5/5 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..284		3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810