Protein Alignment Dfd and NKX2-3

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 76/328 - (23%)
• Similarity: 121/328 - (36%)
• Gaps: 92/328 - (28%)

  Fly   240 MDLPLQCSSTEPPTNTALGLQEL-----GLKLEKRIEE---------AVPAGQQLQELGMRLRCD 290
            |.||...:||.......|.|::.     |..|:..:|.         |...|.|..:
Human     1 MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSD-------- 57

  Fly   291 DMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLG------------DSDSD----EDLMAETTDG 339
              |.|.|:..|.::|....|   |.:.|...|.|            ||.|:    |:......|.
Human    58 --GGEEDEEDEGEKLSYLNS---LAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDR 117

  Fly   340 ERIIYPWMKKIHVAG---VANGSYQPGMEPKRQ-RTAYTRHQILELEKEFHYNRYLTRRRRIEIA 400
            .:......|.:..||   .|..|.:|....:|: |..:::.|:.|||:.|...|||:...|..:|
Human   118 SQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLA 182

  Fly   401 HTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQ 465
            .:|.|:..|:||||||||.|.|:..        :.|:::...:..|   .|.:|.|
Human   183 SSLKLTSTQVKIWFQNRRYKCKRQR--------QDKSLELGAHAPP---PPPRRVA--------- 227

  Fly   466 QQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQQHLSNNNNNGS 530
                       .||:   :| |....:...:.:.|.|..:.|:..:.:|:|.          .|.
Human   228 -----------VPVL---VR-DGKPCVTPSAQAYGAPYSVGASAYSYNSFPA----------YGY 267

  Fly   531 GNN 533
            ||:
Human   268 GNS 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	23/51 (45%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		5/20 (25%)
		HOX	148..204	CDD:197696	24/55 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910