DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Hoxa2

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_034581.1	Gene:	Hoxa2 / 15399	MGIID:	96174	Length:	372	Species:	Mus musculus

Alignment Length:	234	Identity:	72/234 - (30%)
Similarity:	98/234 - (41%)	Gaps:	62/234 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 YPWMKKIHVA-----------------------GVANGSYQPGMEPKRQRTAYTRHQILELEKEF 385
            |||||:...|                       .:|:||   |...:|.|||||..|:|||||||
Mouse    97 YPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADGS---GGGSRRLRTAYTNTQLLELEKEF 158

  Fly   386 HYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGN------- 443
            |:|:||.|.||:|||..|.|:|||:|:||||||||.|:..:....:|...|..:...:
Mouse   159 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKVEEDE 223

  Fly   444 --------PTPVAKKPTKRAASKKQQQAQQQQQS---QQQQTQQTPVMNECIRSDSLESIGDVSS 497
                    ...|:....:|.....||.|..|||:   ....:|..||........:|:.....|
Mouse   224 EEKSLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQTFPVSPLTSNEKNLKHFQHQS- 287

  Fly   498 SLGNPPYIPAAPETTSSYPGSQQHLSNNNNNGSGNNNNN 536
                    |..|...|:.         ..|.|:|.||::
Mouse   288 --------PTVPNCLSTM---------GQNCGAGLNNDS 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	37/51 (73%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..95
		Antp-type hexapeptide	96..101		3/3 (100%)
		Homeobox	143..195	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..225		3/30 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810