DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Hmx1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_034575.1	Gene:	Hmx1 / 15371	MGIID:	107178	Length:	332	Species:	Mus musculus

Alignment Length:	257	Identity:	68/257 - (26%)
Similarity:	93/257 - (36%)	Gaps:	89/257 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 GYGPAANVPNTSNGGG-----GGGSGAVLGGGAVGGSANGY---YGGYGGGYGTANGSVGSTHSQ 231
            |.||.......:.|.|     |.|....||   .||:...|   :||||||.
Mouse    73 GSGPGGEARARALGLGPRPPPGPGPPFALG---CGGTTRWYPRVHGGYGGGL------------- 121

  Fly   232 GHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSEN 296
              ||.:...|        .|.|...:|          |.|.|.|            ||...|:..
Mouse   122 --SPDTSDRD--------SPETGEEMG----------RAESAWP------------RCPGPGTVP 154

  Fly   297 DDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQ 361
            .:::.:                     |.:...|: .||..:...          ||..|.|..:
Mouse   155 REVTTQ---------------------GPATGGEE-AAELAEAPA----------VAAAATGEAR 187

  Fly   362 PGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKK 423
            .|.. |:.||.::|.|:.:||..|...|||:...|..:|.:|.|:|.|:||||||||.|||:
Mouse   188 GGRR-KKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKR 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	25/51 (49%)
Hmx1	NP_034575.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..170		33/166 (20%)
		Homeobox	194..247	CDD:278475	25/52 (48%)
		HMX family specific domain 1	251..261
		HMX family specific domain 2	264..277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910