Protein Alignment Dfd and NKX2-6

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 72/297 - (24%)
• Similarity: 108/297 - (36%)
• Gaps: 98/297 - (32%)

  Fly   251 PPTNTALGLQELGLKLEKRIEEAVPAG----------QQLQELGMRLRCDDMGSENDDMSEEDRL 305
            |.|:|...:::: |:||:  |.:.||.          :..|.|  |:..:..|||
Human     5 PVTSTPFSVKDI-LRLER--ERSCPAASPHPRVRKSPENFQYL--RMDAEPRGSE---------- 54

  Fly   306 MLDRSPDELGSNDNDDDLGDS-----------DSDEDLMAETTDGERIIYP--WMKKIHVAGVAN 357
                 ....|....|..|..|           :.|.:.|.|...|.....|  ...::...||.|
Human    55 -----VHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGN 114

  Fly   358 G--------SYQPGMEPKRQ-RTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIW 413
            .        |.||....:|: |..:::.|:|.||:.|...|||:...|..:|..|.|:..|:|||
Human   115 SGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIW 179

  Fly   414 FQNRRMKWKKDNKLPNTKNVRKKTVDANGNP-TPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQT 477
            |||||.|.|:..        :.|:::..|:| ||      :|.|                    .
Human   180 FQNRRYKCKRQR--------QDKSLELAGHPLTP------RRVA--------------------V 210

  Fly   478 PVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSS 514
            ||:           :.|....||..|..||.|...|:
Human   211 PVL-----------VRDGKPCLGPGPGAPAFPSPYSA 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	23/51 (45%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		25/129 (19%)
		HOX	132..188	CDD:197696	24/55 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910