DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and AgaP_AGAP000190

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_310944.5	Gene:	AgaP_AGAP000190 / 1272074	VectorBaseID:	AGAP000190	Length:	493	Species:	Anopheles gambiae

Alignment Length:	422	Identity:	98/422 - (23%)
Similarity:	141/422 - (33%)	Gaps:	149/422 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHSMH 81
            :|.|:|:.:.........|....||              .|||.|    |||||||..|.|...:
Mosquito    18 TPSSLGDTMSDSAGLCLQDLVGVNG--------------TGGGGG----GGGGAGGTGGGPGGAN 64

  Fly    82 PADMVSDYM---AHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASA-------GGYSS----NYA 132
              :.::|::   ..||.||:|     |||   |......|...:||       ||.:|    :..
Mosquito    65 --NTLADHLHGTGAHHGPHTH-----HSL---HDGLVSGGVSVSSAITSLMSPGGINSGGLGHLH 119

  Fly   133 NATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAV 197
            :..|....|.|.|.|.||      ||     .:.|:| :|.......|..
Mosquito   120 HGAPDLSAHHHHHHHHHQ------HH-----HSSALH-EPLEKLKLWAET--------------- 157

  Fly   198 LGGGAVGGSANGYYGGYGGGYGTANGSVGS-THSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQE 261
                          |.:.....|...||.| .|:|...|.|.    |...||.:...:.:..:.|
Mosquito   158 --------------GDFRENSHTGMTSVSSIDHAQMGFPASS----PRNRSSRDRKNDVSRCINE 204

  Fly   262 LGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDS 326
            ..:|.|                          :.:..||.|                  |..|..
Mosquito   205 ASVKTE--------------------------NLSSGMSHE------------------DGTGSV 225

  Fly   327 DSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYL 391
            .....:..:.|||.:                 :.:.....:||||.:|..|:.|||:.|..|||.
Mosquito   226 APGTTIQQDGTDGTK-----------------NDKKNKRQRRQRTHFTSQQLHELEQTFSRNRYP 273

  Fly   392 TRRRRIEIAHTLVLSERQIKIWFQNRRMKWKK 423
            ....|.|||....|:|.::::||:|||.||:|
Mosquito   274 DMSTREEIAMWTNLTEARVRVWFKNRRAKWRK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	23/51 (45%)
AgaP_AGAP000190	XP_310944.5	Homeobox	252..304	CDD:278475	23/51 (45%)
AgaP_AGAP000190	XP_310944.5	OAR	445..460	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910