DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Cdx1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_034010.3	Gene:	Cdx1 / 12590	MGIID:	88360	Length:	268	Species:	Mus musculus

Alignment Length:	114	Identity:	53/114 - (46%)
Similarity:	67/114 - (58%)	Gaps:	13/114 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 RIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVL 405
            |..|.||::...|....||.:...:.| .|..||.||.|||||||||:||:|.||:.|:|..|.|
Mouse   130 RTPYEWMRRSVAAAGGGGSGKTRTKDK-YRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGL 193

  Fly   406 SERQIKIWFQNRRMKWKKDNK--------LPNTKNVRKKTVDANGNPTP 446
            :|||:||||||||.|.:|.||        ||.|    :..:..:|.|||
Mouse   194 TERQVKIWFQNRRAKERKVNKKKQQQQQPLPPT----QLPLPLDGTPTP 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	35/51 (69%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..152		7/21 (33%)
		Caudal_act	13..138	CDD:282574	4/7 (57%)
		Interaction with DNA. /evidence=ECO:0000250\|UniProtKB:P47902	157..178		14/20 (70%)
		Homeobox	158..210	CDD:278475	35/51 (69%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250\|UniProtKB:P47902	196..207		9/10 (90%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..268		10/34 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910