DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Barhl1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_476450.1	Gene:	Barhl1 / 117232	RGDID:	620648	Length:	327	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	55/215 - (25%)
Similarity:	90/215 - (41%)	Gaps:	43/215 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 SPHSQMMDLPLQCSSTEPP------TNTALGLQELGLKLEKRIEE---AVPAGQQLQELGMRLR- 288
            ||.|:...   .|||...|      |:|:......|..|:..::.   :.||..:.......:|
  Rat    39 SPRSESSS---DCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRD 100

  Fly   289 ----------CDDMGSENDDMSEE--DRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGER 341
                      |....|.....:.|  .||......|.....|.......|||:..:..|   |:|
  Rat   101 ILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEE---GDR 162

  Fly   342 IIYPWMKKIHVAGVANGSYQPGM---EPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTL 403
                        .:::....|.:   :|::.|||:|.||:.:||:.|...:||:.:.|:|:|.:|
  Rat   163 ------------EISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASL 215

  Fly   404 VLSERQIKIWFQNRRMKWKK 423
            .|::.|:|.|:||||.|||:
  Rat   216 NLTDTQVKTWYQNRRTKWKR 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	24/51 (47%)
Barhl1	NP_476450.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..90		13/53 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..181		14/82 (17%)
		Homeobox	182..235	CDD:395001	25/52 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910