Protein Alignment Dfd and Barhl2

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001005477.1
• Gene: Barhl2 / 104382
• MGIID: 1859314
• Length: 384
• Species: Mus musculus
• Alignment Length: 524
• Identity: 108/524 - (20%)
• Similarity: 169/524 - (32%)
• Gaps: 202/524 - (38%)

  Fly    45 MTASTGHMSGAVGGGAGVGSV----GGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHSHSHSHTH 105
            |||    |.||.|...|:.::    |.|..|.|.|...|:..| ..:|:.:
Mouse     1 MTA----MEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEA-RTTDFRS-------------- 46

  Fly   106 SLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHS------HPH------AHPHQSLGYYVHH 158
                           ||:....|......|.||.|.|      .||      .|.|     ::||
Mouse    47 ---------------QATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHH-----HLHH 91

  Fly   159 A-----PEFISAGAVHSDP-----------TNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGS- 206
            :     |..:.|.::...|           ....|.||..|.||       :.:.|....:|.|
Mouse    92 SQQPPPPSAVPAQSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTS-------TSSFLIKDILGDSK 149

  Fly   207 ---ANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEK 268
               |...|          :.||.|.|   |:|..:              :|.|  .:....|||:
Mouse   150 PLAACAPY----------STSVSSPH---HTPKQE--------------SNAA--HESFRPKLEQ 185

  Fly   269 RIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLM 333
                                            |:.:..||:..             |..||....
Mouse   186 --------------------------------EDGKTKLDKRE-------------DPQSDIKCH 205

  Fly   334 AETTDGERIIYPWMKKIHVAGVANGSYQP--GMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRR 396
            ....:|:|.|           .::....|  ..:|::.|||::.||:.:||:.|...:||:.:.|
Mouse   206 GTKEEGDREI-----------TSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDR 259

  Fly   397 IEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGN--------PTPVAKKP-- 451
            :::|..|.|::.|:|.|:||||.|||:...      |..:.:...||        |:|....|
Mouse   260 MDLAAALNLTDTQVKTWYQNRRTKWKRQTA------VGLELLAEAGNYSALQRMFPSPYFYHPSL 318

  Fly   452 -------TKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIG----DVSSSLGNPPYI 505
                   |..||:.....:..:.........|.|::...:    :..:|    ...:.|.||  |
Mouse   319 LGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVL----IHGLGPGGQPALNPLSNP--I 377

  Fly   506 PAAP 509
            |..|
Mouse   378 PGTP 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	23/55 (42%)
Barhl2	NP_001005477.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		37/171 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..235		24/165 (15%)
		Homeodomain	230..286	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..384		6/20 (30%)