DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and Hoxb2

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_598793.2	Gene:	Hoxb2 / 103889	MGIID:	96183	Length:	354	Species:	Mus musculus

Alignment Length:	189	Identity:	65/189 - (34%)
Similarity:	94/189 - (49%)	Gaps:	39/189 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 YPWMKK--------------------IHVAGVANGSYQPGME------PKRQRTAYTRHQILELE 382
            :||||:                    :..:.|.:.|..||:.      .:|.|||||..|:||||
Mouse    93 FPWMKEKKSTKKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELE 157

  Fly   383 KEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKD---NKLPNTKNVRKKTVDANGNP 444
            ||||:|:||.|.||:|||..|.|:|||:|:||||||||.|:.   .:.|..:.......|..|.|
Mouse   158 KEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEP 222

  Fly   445 TPVAKKPTKR---AASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLG 500
               |::||..   .|:.:.::|........|..:..|  ...:.:.:|||:|  :||.|
Mouse   223 ---AEEPTVSPGDVATHRLREACFHPAEAAQGPRGAP--PSALPATTLESVG--ASSPG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	37/51 (73%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..143		8/49 (16%)
		Antp-type hexapeptide	92..97		2/3 (67%)
		Homeobox	145..197	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		11/40 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..295		9/33 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810