DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and prrx1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_004913839.1	Gene:	prrx1 / 100494324	XenbaseID:	XB-GENE-484663	Length:	248	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	41/197 - (20%)
Similarity:	79/197 - (40%)	Gaps:	39/197 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 PAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDG 339
            |.|.:| |..:....|::.::. :.|....|.|:.:.:.:|:...|   |..::...|:..
Frog    15 PLGSRL-ESPITASLDNLQAKK-NFSVSHLLDLEEAGEMVGAQAED---GSGEAGRSLLES---- 70

  Fly   340 ERIIYPWMKKIHVAGVANGSYQPGME-------------PKRQRTAYTRHQILELEKEFHYNRYL 391
                         .|:.:||..|..|             .:|.||.:...|:..||:.|....|.
Frog    71 -------------PGLTSGSDTPQQENEQMNAEQKKKRKQRRNRTTFNSSQLQALERVFERTHYP 122

  Fly   392 TRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKL----PNTKNVRKKTVDANGNPTPVAKKPT 452
            ....|.::|..:.|:|.::::||||||.|::::.:.    .|...::....|......|:..:|.
Frog   123 DAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYAGDVTAVEQPIVPRPA 187

  Fly   453 KR 454
            .|
Frog   188 PR 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	18/51 (35%)
prrx1	XP_004913839.1	Homeobox	102..154	CDD:365835	17/51 (33%)
prrx1	XP_004913839.1	OAR	221..238	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910