DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and arx

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_002933659.1	Gene:	arx / 100486727	XenbaseID:	XB-GENE-483940	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	71/290 - (24%)
Similarity:	107/290 - (36%)	Gaps:	94/290 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 YGTANGSVGSTHSQGHS------PHSQMMDLPLQCSSTEPPT--NTALGLQ---ELGLKLEKRI- 270
            ||...|| |..|.|..:      |.|:..|..|........|  |.:|.:.   ::.:...|..
Frog    85 YGPVGGS-GRIHLQAVADARSGVPRSEKTDRILLLGGAGENTWDNHSLKISQAPQVSISRSKSYR 148

  Fly   271 --------EEAVPAG-----QQLQELGMRLRC----DDMGS--------ENDDMSEEDRLMLDRS 310
                    ||..|.|     ||..:......|    |.:|:        ::||..:||....:..
Frog   149 ENSAPLLREEHSPEGLLQQSQQQIQTSATTACTSLQDRLGALSQSPRDEDDDDEEDEDEEEEEEE 213

  Fly   311 PDELGSNDNDDDLGD-----------------------------SDSD----EDLM-----AETT 337
            .||.....|.::..:                             :|::    |:||     |:..
Frog   214 EDEANKQHNPNNSSNPNRAHLQEQQHPQFQSQQSQQQQPPPGCGTDAELSPKEELMLHSSDADGK 278

  Fly   338 DGERIIYPWMKKIHVAGVANGSYQPGM---EPKRQRTAYTRHQILELEKEF---HYNRYLTRRRR 396
            |||.         .|...|....:.||   :.:|.||.:|.:|:.|||:.|   ||....||.
Frog   279 DGED---------SVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE-- 332

  Fly   397 IEIAHTLVLSERQIKIWFQNRRMKWKKDNK 426
             |:|..|.|:|.::::||||||.||:|..|
Frog   333 -ELAMRLDLTEARVQVWFQNRRAKWRKREK 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	24/54 (44%)
arx	XP_002933659.1	Homeobox	305..358	CDD:365835	25/55 (45%)
arx	XP_002933659.1	OAR	500..518	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910