DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hoxc3

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_002936696.1	Gene:	hoxc3 / 100190990	XenbaseID:	XB-GENE-5997986	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	473	Identity:	117/473 - (24%)
Similarity:	165/473 - (34%)	Gaps:	197/473 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 GGSANGYYGGYGGGY--------------------GTANGSVG--STHS-------------QGH 233
            ||.  |:.|..|.||                    .|||||..  ..||             |..
Frog    16 GGC--GFQGNNGMGYLGQQDYPSEDDYQPPFCLPPDTANGSASHKGEHSIKGIDFHLSEVSEQAQ 78

  Fly   234 SPHSQMMDLPL-QCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSEND 297
            .|.|...|.|| :.:||:..|:.                                  ...|..:.
Frog    79 QPKSPNSDSPLPKSASTQSCTSK----------------------------------KSTGPVSS 109

  Fly   298 DMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQP 362
            |::         ||::.....|                   ..:.|:||||:     ....|.|.
Frog   110 DVT---------SPNKKSKGSN-------------------MPKQIFPWMKE-----TRQNSKQK 141

  Fly   363 GMEP------------------KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQ 409
            ...|                  ||.|||||..|::|||||||:||||.|.||:|:|..|.|||||
Frog   142 KQAPPPADDAPAVDSSFLSSASKRARTAYTNSQLVELEKEFHFNRYLCRPRRLEMAKLLNLSERQ 206

  Fly   410 IKIWFQNRRMKWKKDNK-------------------LPNTKNVRKKTVDAN-GNPTPVA-----K 449
            |||||||||||:|||:|                   :|.:.|:   .:|.: |...|:|     |
Frog   207 IKIWFQNRRMKFKKDHKGKGGGGSPGGLSPSSSPSLMPYSGNL---PLDGDCGYEVPMATGAYNK 268

  Fly   450 KP------TKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAA 508
            .|      |..:|...:..:.|::...|                ||....|..|..|:..|
Frog   269 SPGNMYGLTAYSAPLFEGPSAQKRYGPQ----------------SLAPEYDPHSMQGDNNY---- 313

  Fly   509 PETTSSYPGSQQHLSNNNNNGSGN-------NNNNNNNNNSNLNNNNNNNQMG-------HTNLH 559
              .||..|..|.:|.|...|||.:       :.::.:.:.|......:.:.:|       :|:||
Frog   314 --DTSGLPNGQGYLGNYLENGSESCSMFSLPHPSSESMDYSCAAQTPSKHHLGPCDPHPTYTDLH 376

  Fly   560 GH----LQQQQSDLMTNL 573
            .|    ...|:..::|:|
Frog   377 IHPVPQACSQEPPVLTHL 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	39/51 (76%)
hoxc3	XP_002936696.1	Homeobox	167..220	CDD:395001	39/52 (75%)
hoxc3	XP_002936696.1	DUF4074	335..392	CDD:404218	7/56 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910