Protein Alignment Dfd and nkx2-5

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001116891.1
• Gene: nkx2-5 / 100144646
• XenbaseID: XB-GENE-487966
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 362
• Identity: 86/362 - (23%)
• Similarity: 142/362 - (39%)
• Gaps: 94/362 - (25%)

  Fly   229 HSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMG 293
            |..|.||    ||:..:             |:.....|....:|..|....|.||
 Frog    22 HQSGLSP----MDITSR-------------LENSSCMLSTFKQEPYPGTPCLSEL---------- 59

  Fly   294 SENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKI-HVAGVAN 357
              .:::::.|.   .:.|.....:....:..:.||.:|    ..|.::.|.|..|.: |....|.
 Frog    60 --TEELAQRDS---SKGPSPFPGSFFVKNYLEMDSSKD----PKDDKKDICPLQKTLEHDKREAE 115

  Fly   358 GSYQPGMEPKRQ-RTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKW 421
            ...:|....:|: |..:::.|:.|||:.|...:||:...|..:|:.|.|:..|:||||||||.|.
 Frog   116 DPERPRQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRRYKC 180

  Fly   422 KKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRS 486
            |:..        :.:|::..|.|      |.:|.|                    .||:   :|
 Frog   181 KRQR--------QDQTLEMVGLP------PPRRIA--------------------VPVL---VR- 207

  Fly   487 DSLESIGDVSSSLGNPPY-IPAAPETTSSYPGSQQHLSNNNNNG-SGNNNNNNNNNNSNLNNNNN 549
            |....:|:  ||..|.|| :...|.:.::||.    .||.:|.. ||:.|.:.::..|....:..
 Frog   208 DGKPCLGE--SSPYNSPYNVSINPYSYNTYPA----YSNYSNPACSGSYNCSYSSMPSMQPTSAG 266

  Fly   550 NNQMGHTNLHGHLQQQQSDLMTNLQLHIKQDYDLTAL 586
            ||.|..:         ..||.| :|..|:|...::||
 Frog   267 NNFMNFS---------VGDLNT-VQTPIQQASGVSAL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	22/51 (43%)
nkx2-5	NP_001116891.1	Homeobox	132..182	CDD:365835	21/49 (43%)
		COG5576	<133..235	CDD:227863	39/141 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910