DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and shox2

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001093694.1	Gene:	shox2 / 100101703	XenbaseID:	XB-GENE-480993	Length:	311	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	55/261 - (21%)
Similarity:	84/261 - (32%)	Gaps:	108/261 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 VHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQG 232
            :.|.|..|..|..        |.|.....:.|...:||...|  ||.|||              .
Frog    29 LESGPARGKEPGC--------GEGAREDGLAGNRCIGGGGGG--GGGGGG--------------A 69

  Fly   233 HSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSEND 297
            .||                       :.||.|.:|:..|...|   :|.|:...::
Frog    70 RSP-----------------------VLELDLSVERIRESGSP---KLTEVSPEIK--------- 99

  Fly   298 DMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQP 362
                                         :..|:|..:..:.|.                   |.
Frog   100 -----------------------------ERKEELKQQALEEEG-------------------QT 116

  Fly   363 GMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKK-DNK 426
            .::.:|.||.:|..|:.|||:.|....|.....|.|::..|.|||.::::||||||.|.:| :|:
Frog   117 KIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQ 181

  Fly   427 L 427
            |
Frog   182 L 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	22/51 (43%)
shox2	NP_001093694.1	Homeobox	123..177	CDD:365835	22/53 (42%)
shox2	NP_001093694.1	OAR	292..307	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910