DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hoxd10

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_031749087.1	Gene:	hoxd10 / 100038085	XenbaseID:	XB-GENE-485204	Length:	274	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	102/240 - (42%)	Gaps:	50/240 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 YGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQ----CSSTEPPTNTALGLQELGLKLEKRIEEAV 274
            |.|.|.:...|....|.....|.::..|:..:    |:...||::.:.....:|.      ...:
Frog    74 YRGTYPSYYPSEEVMHRDLIQPANRRSDMLFKSDSVCNHHGPPSSQSNFYSSVGR------NGIL 132

  Fly   275 PAG-----QQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMA 334
            |.|     ...|..|.::..::..:::|..:.........:.|:..:||:...
Frog   133 PQGFDQFYDSSQNQGYQVGMEEQPAKSDPKATNAPTKAPSTQDKKVTNDSSPG------------ 185

  Fly   335 ETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEI 399
             |..||            |..:|.|....:  :::|..|:::||.|||:||.:|.|:.:.:|:::
Frog   186 -TPSGE------------AEKSNSSASQRL--RKKRCPYSKYQIRELEREFFFNVYINKEKRLQL 235

  Fly   400 AHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNP 444
            :..|.|::||:||||||||||.||.|        |.:.....|||
Frog   236 SRMLNLTDRQVKIWFQNRRMKEKKLN--------RDRLQYFTGNP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	26/51 (51%)
hoxd10	XP_031749087.1	DUF3528	41..163	CDD:403310	16/94 (17%)
hoxd10	XP_031749087.1	Homeobox	205..259	CDD:395001	26/53 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000