DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and opcml

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001072487.1	Gene:	opcml / 779942	XenbaseID:	XB-GENE-5831850	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	345	Identity:	96/345 - (27%)
Similarity:	144/345 - (41%)	Gaps:	56/345 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PDMARLRLLIGLIFCLAIS-LDSVLSAPVIS------QISKDVVASVGDSVEFNCTVEEVGQLSV 64
            |..|.|...:..:|..|:: |.|:...||.|      :...:|....|||....|||:. ....|
Frog     5 PAAAHLYHHVCWMFGAALTVLLSITGVPVRSGDAGFPKAMDNVTVRQGDSAILRCTVDN-RVTRV 68

  Fly    65 SWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLV 129
            :|..|       |.:|...|.....|.|  |.:....|:.   |:..|||:::.|.|||.|.|..
Frog    69 AWLNR-------STILYTGNDKWSIDPR--VVLLANTKSQ---YSIEIQNVDIYDEGPYTCSVQT 121

  Fly   130 SATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISW----AREHNAVMP 190
            ....| |.::.|.::..|.|. |......|.||..:.|.|.|.|.|:|.::|    .:.|..|..
Frog   122 DNHPK-TSRVHLIVQVAPQIL-NISSDITVNEGSTVALRCLATGRPEPAVTWRHFTGKSHRFVSD 184

  Fly   191 AGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSA 255
                   :..|.|..:.|...|.|.|.|.|....||.|.:||.|.:.|.|:..|...|.: ....
Frog   185 -------DEYLEITGITRDQSGQYECSAANDVSAPDIRKVRVTVNYPPYISDTRNTGASL-GQKG 241

  Fly   256 ELECSVQGYPAPTVVWHK---------NGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFG 311
            .|.||....|.....|::         :||.:::..|             .|:|...:|.|:|:|
Frog   242 ILRCSASAVPLAEFQWYREETRLANGLDGVRIENKDH-------------MSILTFFNVSEKDYG 293

  Fly   312 DYYCNATNKLGHADARLHLF 331
            :|.|.|:||||:::|.:.|:
Frog   294 NYTCVASNKLGNSNASVILY 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	33/115 (29%)
		Ig	37..127	CDD:299845	26/89 (29%)
		IG_like	154..234	CDD:214653	25/83 (30%)
		IGc2	161..223	CDD:197706	19/65 (29%)
		I-set	254..330	CDD:254352	22/84 (26%)
		IGc2	254..322	CDD:197706	19/76 (25%)
opcml	NP_001072487.1	Ig	46..134	CDD:325142	30/101 (30%)
		Ig_3	138..207	CDD:316449	22/76 (29%)
		ig	228..312	CDD:278476	24/97 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010