DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and DIP-delta

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001097508.2	Gene:	DIP-delta / 5740816	FlyBaseID:	FBgn0085420	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	93/340 - (27%)
Similarity:	151/340 - (44%)	Gaps:	36/340 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RLLIGLIFCLAISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNS 77
            |.::.||:...:....::..|..:|...:|..:||......|.||.:|...|:|.    ..|...
  Fly    24 RRIMFLIYMTNLVTHVMMDEPRFAQPIPNVTVAVGRDANLPCVVEHLGGYKVAWI----HIDRQM 84

  Fly    78 VVLSMRNILS-LPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSL 141
            ::...|:::| :|  ||::|.|:.      .:...:......|.|.|.||  |:....:::...|
  Fly    85 ILTIHRHVISRIP--RYSITYTDN------TWLLHVNQAHQDDRGYYMCQ--VNTNPMISQVGYL 139

  Fly   142 QIKTPPVI--AENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAE------ 198
            |:..||.|  .|:||.|..|.|.||:.:||.|:|||.|.|.|.||.      |..:..|
  Fly   140 QVVVPPNILDIESTPSSVAVRENQNINMTCRADGFPAPKIIWRRED------GEEIAVEKKKKVL 198

  Fly   199 ----PTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELEC 259
                ..|.:..|.|.:.|.|.|||.||......:.|.::|||.|.|.|....:.........::|
  Fly   199 VYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDC 263

  Fly   260 SVQGYPAPTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHA 324
            ..:.:|...:.|..|.|.:..|:.::...|.:|...... |.|.::...|||:|.|.:.|.||..
  Fly   264 HTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYRAHMK-LTIRNLQYGDFGNYRCISKNSLGET 327

  Fly   325 DARLHLFQTVIPVPS 339
            :..:.:::  ||:||
  Fly   328 EGSIRVYE--IPLPS 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/110 (24%)
		Ig	37..127	CDD:299845	22/90 (24%)
		IG_like	154..234	CDD:214653	30/89 (34%)
		IGc2	161..223	CDD:197706	26/71 (37%)
		I-set	254..330	CDD:254352	18/75 (24%)
		IGc2	254..322	CDD:197706	16/67 (24%)
DIP-delta	NP_001097508.2	IG	51..143	CDD:214652	25/105 (24%)
		Ig	145..238	CDD:416386	34/98 (35%)
		Ig strand A	145..149	CDD:409353	2/3 (67%)
		Ig strand A'	154..159	CDD:409353	2/4 (50%)
		Ig strand B	165..172	CDD:409353	2/6 (33%)
		Ig strand C	178..183	CDD:409353	2/4 (50%)
		Ig strand C'	185..187	CDD:409353	0/7 (0%)
		Ig strand D	195..199	CDD:409353	0/3 (0%)
		Ig strand E	203..209	CDD:409353	1/5 (20%)
		Ig strand F	216..223	CDD:409353	4/6 (67%)
		Ig strand G	230..238	CDD:409353	1/7 (14%)
		Ig	242..333	CDD:416386	21/91 (23%)
		Ig strand A'	250..253	CDD:409353	0/2 (0%)
		Ig strand B	259..266	CDD:409353	1/6 (17%)
		Ig strand C	272..277	CDD:409353	1/4 (25%)
		Ig strand C'	281..283	CDD:409353	0/1 (0%)
		Ig strand D	289..293	CDD:409353	0/3 (0%)
		Ig strand E	295..305	CDD:409353	2/10 (20%)
		Ig strand F	314..322	CDD:409353	3/7 (43%)
		Ig strand G	325..334	CDD:409353	1/8 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	5	4.820