DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and aebp1b

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	311	Identity:	62/311 - (19%)
Similarity:	113/311 - (36%)	Gaps:	108/311 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 VLSMRN-------ILSLPDQRYNVT-VTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKV 135
            :|.:||       .|||....:.|. :||..|: ...:|.|.|::|..:         |::.|.:
Zfish     1 MLGLRNQKTLVVLCLSLLVPSWEVNGLTEHSKS-EISHTDREQHVEDRN---------VTSVEDL 55

  Fly   136 TKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAE-- 198
                 ||:|..|      |.:| :..||:.:|.|..:...| .|:|      |.|.|..:|.:
Zfish    56 -----LQVKIIP------PYAT-IEVGQHKQLLCKVSSDAK-NINW------VSPNGEKVLTKHG 101

  Fly   199 -----------PTLRIRSVHRMDRGGYYCIAQNGEGQP----------------------DKRLI 230
                       .:|.:.:.:..:.|.|.|:|.||:.:.                      :|||.
Zfish   102 NLKVHNHGSVLSSLTVLNANLNNAGIYKCVATNGDTESQATVKLDIILKRMRRDTDRKGREKRLK 166

  Fly   231 RVEVEFRPQIA--VQRPKI----------AQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRH 283
            ..:...:|:.:  .::||.          .:....:.|...:|    |.|.|.....||::....
Zfish   167 EPKPSKKPKASKPTKKPKSEKKGKGEKGGKKKGKKNREESTTV----ATTTVAPTTTVPMEYEEF 227

  Fly   284 HE-----------VANTASSSGTTTS--------VLRIDSVGEED-FGDYY 314
            ::           .|.|.:.:.|||:        :..:|...:.| :.||:
Zfish   228 YDPEPDQYWDEDFPAETTTVARTTTTPTEKTKDFIPDMDEYSQPDSYDDYW 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	17/71 (24%)
		Ig	37..127	CDD:299845	14/55 (25%)
		IG_like	154..234	CDD:214653	23/114 (20%)
		IGc2	161..223	CDD:197706	18/74 (24%)
		I-set	254..330	CDD:254352	16/81 (20%)
		IGc2	254..322	CDD:197706	16/81 (20%)
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	24/104 (23%)
		IG_like	62..145	CDD:214653	21/96 (22%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900