DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and igsf9ba

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	334	Identity:	84/334 - (25%)
Similarity:	139/334 - (41%)	Gaps:	53/334 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LIFCLAISLDSVLS--------APVISQISKDVVASVGDSVEFNCTVEEV--GQLS---VSWAKR 69
            :|:.:|..:.||.|        |..:.:..:.|.|..|:||...|.|...  ||.:   |.|.|
Zfish     1 MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFK- 64

  Fly    70 PSESDTNSVVLSMRNILSLP-----DQRYNVTVTEGPKTGSAIY----TFRIQNIEVSDMGPYEC 125
                            ..:|     :.|:.....:....|.|..    :.:|:.:...|.|.|||
Zfish    65 ----------------FGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYEC 113

  Fly   126 QVLVSATEKVT----KKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHN 186
            :||:...:..|    ..:.|.:..||..::..|:.....||.::.|||.|.|.|||.::|.||.:
Zfish   114 RVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGD 178

  Fly   187 AVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMV 251
            .:.....:.:::.:|.::::.|.|||.|.|.|.:.:|:. ....|:.|:..|.|......|...:
Zfish   179 QLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEA-LHTTRLLVQGPPYIVTPPENITVNI 242

  Fly   252 SHSAELECSVQGYPAP---TVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDY 313
            |.:|:..|..:.||..   |..|.::.|..::.....|  .....||    |.|..|..||.|.|
Zfish   243 SQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRV--RIFIDGT----LIIYRVKPEDAGKY 301

  Fly   314 YCNATNKLG 322
            .|:.:|.||
Zfish   302 TCSPSNSLG 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/127 (20%)
		Ig	37..127	CDD:299845	22/103 (21%)
		IG_like	154..234	CDD:214653	24/79 (30%)
		IGc2	161..223	CDD:197706	21/61 (34%)
		I-set	254..330	CDD:254352	21/72 (29%)
		IGc2	254..322	CDD:197706	19/70 (27%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	22/101 (22%)
		I-set	139..225	CDD:254352	25/86 (29%)
		I-set	229..321	CDD:333254	25/88 (28%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810