DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ama and Ntm

DIOPT Version :9

Sequence 1:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:301 Identity:89/301 - (29%)
Similarity:132/301 - (43%) Gaps:27/301 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 DVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGS 105
            :|....|:|....||::. ....|:|..|       |.:|...|.....|.|  |.:....:|. 
  Rat    44 NVTVRQGESATLRCTIDN-RVTRVAWLNR-------STILYAGNDKWCLDPR--VVLLSNTQTQ- 97

  Fly   106 AIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCH 170
              |:..|||::|.|.|||.|.|......| |.::.|.::..|.|.| ......:.||.|:.|||.
  Rat    98 --YSIEIQNVDVYDEGPYTCSVQTDNHPK-TSRVHLIVQVSPKIVE-ISSDISINEGNNISLTCI 158

  Fly   171 ANGFPKPTISWAREHNAVMP-AGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEV 234
            |.|.|:||::|..    :.| |.|.:..:..|.|:.:.|...|.|.|.|.|....|..|.::|.|
  Rat   159 ATGRPEPTVTWRH----ISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVTV 219

  Fly   235 EFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPL-QSSRHHEVANTASSSGTTTS 298
            .:.|.|: :.......|.....|:|.....|:....|.|:...| :..:..:|.|....|..|  
  Rat   220 NYPPYIS-EAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSRLT-- 281

  Fly   299 VLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIPVPS 339
               ..:|.|.|:|:|.|.|:|||||.:|.:.||:...|..|
  Rat   282 ---FFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSS 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AmaNP_731114.2 I-set 33..143 CDD:254352 29/101 (29%)
Ig 37..127 CDD:299845 25/85 (29%)
IG_like 154..234 CDD:214653 26/80 (33%)
IGc2 161..223 CDD:197706 23/62 (37%)
I-set 254..330 CDD:254352 23/76 (30%)
IGc2 254..322 CDD:197706 19/68 (28%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 29/101 (29%)
Ig strand A' 44..49 CDD:409353 1/4 (25%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 0/4 (0%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 4/18 (22%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 14/38 (37%)
Ig strand D 87..94 CDD:409353 2/8 (25%)
Ig strand E 97..103 CDD:409353 1/8 (13%)
Ig strand F 110..118 CDD:409353 4/7 (57%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 136..205 CDD:404760 25/73 (34%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 4/8 (50%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 25/89 (28%)
putative Ig strand A 223..229 CDD:409353 2/6 (33%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/8 (25%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337178
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR42757
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
76.950

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