DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ama and opcml

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	311	Identity:	82/311 - (26%)
Similarity:	131/311 - (42%)	Gaps:	53/311 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SQISKDVVASVGDSVEFNCTVE-EVGQLSVSWAKRPSESDTNSVVLSM--RNILSLPDQRYNVTV 97
            |.:..::....|||....|::: :|.:  |:|..|.:...|.:...|:  |.:|      .|..|
Zfish    36 SYLKDNITVRQGDSAVLKCSMDNKVSR--VAWLNRTTILFTGNEKWSLDPRVVL------LNTAV 92

  Fly    98 TEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKSTLVTEG 162
            .|        |:.:|.|:.:.|.|||.|.:|.:...:.| |:.|.::.|..|. |......|.||
Zfish    93 NE--------YSIKILNVNLYDEGPYVCSILTNKKPEST-KVHLIVQVPARIV-NVSTDVSVNEG 147

  Fly   163 QNLELTCHANGFPKPTISW---AREHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQ 224
            .|:.|.|.|.|.|:|:|.|   :.:.|.::..|.:      :.:..:.:...|.|.||..|....
Zfish   148 SNVSLMCLAIGRPEPSILWKFRSSKGNRIVTEGEY------VEMTGITKDMSGSYDCITSNDISP 206

  Fly   225 PDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHK---------NGVPLQS 280
            ||.|.::|.|.:.|.|:..| .....|.....|.|.....|.....|.|         |||.:::
Zfish   207 PDVRTVQVTVNYPPVISRAR-STGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNGVKIEN 270

  Fly   281 SRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLF 331
            ....             |:|...:|.|||:|:|.|.|.|.||..:|.:.|:
Zfish   271 KGKQ-------------SMLTFFNVSEEDYGNYTCVAINTLGITNASIILY 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	28/109 (26%)
		Ig	37..127	CDD:299845	23/92 (25%)
		IG_like	154..234	CDD:214653	23/82 (28%)
		IGc2	161..223	CDD:197706	18/64 (28%)
		I-set	254..330	CDD:254352	22/84 (26%)
		IGc2	254..322	CDD:197706	19/76 (25%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	27/104 (26%)
		IG_like	41..129	CDD:214653	27/104 (26%)
		IG_like	139..216	CDD:214653	23/82 (28%)
		IGc2	146..202	CDD:197706	17/61 (28%)
		I-set	219..307	CDD:254352	26/101 (26%)
		ig	223..307	CDD:278476	24/97 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42757
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.880