DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and negr1

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_009300786.1	Gene:	negr1 / 445374	ZFINID:	ZDB-GENE-040822-27	Length:	360	Species:	Danio rerio

Alignment Length:	331	Identity:	94/331 - (28%)
Similarity:	144/331 - (43%)	Gaps:	38/331 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LIGLIFCLAISLDSVLSAPV---ISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTN 76
            |..:|..|...|.|.|.|..   .:..|:.||:..||:....|.:.: |....:|..|.|
Zfish    17 LTAIILSLCCFLPSCLPAGQTVDYTTSSESVVSRQGDTALLRCYLLD-GISKGAWLNRSS----- 75

  Fly    77 SVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSL 141
              ::...|.....|.|.::....|.|..   |:.:||.::|:|.|.|.|.: .|......|.:.|
Zfish    76 --IIYAGNDKWSGDPRVSIVSNVGDKHE---YSLQIQKVDVTDEGVYTCSI-QSERNLHPKLIQL 134

  Fly   142 QIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSV 206
            .:|.||.|.:.:...| |.||.|:.|.|.|:|.|:|.|||..    :.|:.....:...|.|..:
Zfish   135 IVKVPPKIYDISSDIT-VNEGSNVSLICAASGKPEPKISWRH----ISPSARKYESGEYLNITGI 194

  Fly   207 HRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHS------AELECSVQGYP 265
            .|...|.|.|.|:|....||.:.:||.|.|       .|.|.:|.||.      |.|.|.....|
Zfish   195 SRDQAGDYECGAENDIASPDTKTVRVTVNF-------PPAIHEMKSHGVRPGQVALLRCEAAAVP 252

  Fly   266 APTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHL 330
            :|...|:|....:...:...:.|.:|     .|||.:.::.::.:|:|.|.|.|:||.|:|.:.|
Zfish   253 SPVFEWYKGEKRINMGQGIVINNLSS-----RSVLTVKNMTQDRYGNYTCVAVNRLGTANASVPL 312

  Fly   331 FQTVIP 336
            ...:.|
Zfish   313 NPIIEP 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/112 (23%)
		Ig	37..127	CDD:299845	23/89 (26%)
		IG_like	154..234	CDD:214653	27/79 (34%)
		IGc2	161..223	CDD:197706	21/61 (34%)
		I-set	254..330	CDD:254352	21/81 (26%)
		IGc2	254..322	CDD:197706	17/73 (23%)
negr1	XP_009300786.1	Ig	42..121	CDD:299845	23/89 (26%)
		IG_like	44..136	CDD:214653	26/103 (25%)
		I-set	140..222	CDD:254352	29/86 (34%)
		IGc2	153..208	CDD:197706	20/58 (34%)
		IG_like	236..312	CDD:214653	21/80 (26%)
		IGc2	238..304	CDD:197706	17/70 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42757
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850