DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and dpr16

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	53/268 - (19%)
Similarity:	87/268 - (32%)	Gaps:	108/268 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRY- 93
            ||.|.:     :.....|......|.:.:.....:||.:...|.     ::::.:...:.|.|:
  Fly   201 LSLPPL-----NATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEH-----IIAVDHTTFINDARFA 255

  Fly    94 ----NVTVT------------------------------EGPKTGSAIYTFRIQNIEVSDMGPYE 124
                :.|:|                              |...:.|..:|.:|:.:.:.|.|.||
  Fly   256 SLLQSTTLTTLVSGGALSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNLEDAGWYE 320

  Fly   125 CQVLVSATE-KVTKKLSLQIKTP--PVIAENTPKSTLVTEGQNLELTCHANG---FPKPTISWAR 183
            ||:   ||| |::.|:.|.:.||  .:|.:   :...|..|..:||.|...|   .|| .|.|.|
  Fly   321 CQL---ATEPKMSAKVQLFVITPRTELIGD---RQRFVKAGSRVELHCIVRGTLEAPK-YIFWYR 378

  Fly   184 ------------------------------EHN------AVMPAGGHLLAEPTLRIRSVHRMDRG 212
                                          |||      .|:|.           :|.:|   .|
  Fly   379 GDQQVTAENEASGAQSGWYTQIDRNIFGSTEHNRNTIGSLVIPL-----------VRKIH---SG 429

  Fly   213 GYYCIAQN 220
            .|.|..:|
  Fly   430 NYTCEPEN 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/145 (18%)
		Ig	37..127	CDD:299845	18/124 (15%)
		IG_like	154..234	CDD:214653	22/106 (21%)
		IGc2	161..223	CDD:197706	21/99 (21%)
		I-set	254..330	CDD:254352
		IGc2	254..322	CDD:197706
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	25/144 (17%)
		Ig	<298..338	CDD:299845	15/42 (36%)
		IG_like	352..447	CDD:214653	22/101 (22%)
		Ig	358..439	CDD:143165	20/95 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810