DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and ImpL2

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	50/213 - (23%)
Similarity:	80/213 - (37%)	Gaps:	57/213 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 KTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAG------GHLLAEPT-- 200
            ||||...:.       .:|..:|:.|...|...|:|.|...|   :|..      .:.:||..
  Fly    62 KTPPTKLQQ-------ADGATIEIVCEMMGSQVPSIQWVVGH---LPRSELDDLDSNQVAEEAPS 116

  Fly   201 --LRIRSVHRMDR-----GGYYCIAQNGEGQPDKRLIRVEVEFRPQIA----------VQRPKI- 247
              :|:||.|.:|.     ..|.|:.:.|    .|.:....|...|:.:          .|:|:|
  Fly   117 AIVRVRSSHIIDHVLSEARTYTCVGRTG----SKTIYASTVVHPPRSSRLTPEKTYPGAQKPRII 177

  Fly   248 ------AQMVSHSAELECSVQGYPAPTVVW--HKNGVPLQSSRHHEVANTASSSGTTTSVLRIDS 304
                  ..::..:.:|.|.|...|...:.|  ::|...:|..||..:||         ..|.|..
  Fly   178 YTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN---------GDLLISE 233

  Fly   305 VGEEDFGDYYCNATNKLG 322
            :..||.|:|.|.|.|.:|
  Fly   234 IKWEDMGNYKCIARNVVG 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352
		Ig	37..127	CDD:299845
		IG_like	154..234	CDD:214653	20/94 (21%)
		IGc2	161..223	CDD:197706	19/76 (25%)
		I-set	254..330	CDD:254352	21/71 (30%)
		IGc2	254..322	CDD:197706	20/69 (29%)
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900