DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ama and wrapper

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	88/359 - (24%)
Similarity:	154/359 - (42%)	Gaps:	66/359 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LIGLIFCLAISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQL-SVSWAKRPSESDTNSV 78
            :..::.||       |:|.::.|:..:        ::||..:|...:. |:....:..|:||..:
  Fly     5 MCSVVRCL-------LAALILGQVQAE--------LDFNNDLENSQKFKSIPTTVKTYENDTVQL 54

  Fly    79 VLSM----------RNILSLPDQRYNVTVTEGPKTGSAIY----TFRIQNIEVSDMGPYECQVLV 129
            ..::          |:.::|.|.|:    .|.|.....:.    :.::.|::.||.|.|.|: :.
  Fly    55 PCTLNTPFRYVRWHRDDVALVDSRH----PELPPPDRIMLWPNGSLQVANVQSSDTGDYYCE-MN 114

  Fly   130 SATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGG- 193
            |.:..|.::.:::::..|.:.......|....|...|:.|.|.|.|:|.|:|....|.:.|...
  Fly   115 SDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNT 179

  Fly   194 ----HLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHS 254
                .|:    |.|:|  |...|...|:|.||.|:|....:.:.|.|.|::::.:|.:...:...
  Fly   180 GNRQSLI----LEIKS--RNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSR 238

  Fly   255 AELECSVQGYPAPTVVWHKNGVPLQSSRH---HEVANTASSSGTTTSV----------LRIDSVG 306
            |.|||.|:..||.||.|..:|:|:....|   ||     |...|..||          |.:.||.
  Fly   239 AHLECIVEAAPAATVKWFHHGLPVALGAHSTTHE-----SELQTNRSVDHYVNAVRHMLVVKSVR 298

  Fly   307 EEDFGDYYCNATNKLGHADARLHLFQTVIPVPSL 340
            ..|.|.|.|.|:|::......:.|  |..|:|.|
  Fly   299 NADMGQYECRASNQISVKSGSVEL--TGRPMPCL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	22/124 (18%)
		Ig	37..127	CDD:299845	20/104 (19%)
		IG_like	154..234	CDD:214653	24/84 (29%)
		IGc2	161..223	CDD:197706	21/66 (32%)
		I-set	254..330	CDD:254352	28/88 (32%)
		IGc2	254..322	CDD:197706	28/80 (35%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	17/87 (20%)
		IG_like	41..118	CDD:214653	16/81 (20%)
		IG_like	145..218	CDD:214653	23/78 (29%)
		Ig	147..219	CDD:299845	23/77 (30%)
		I-set	224..323	CDD:254352	30/105 (29%)
		IGc2	236..314	CDD:197706	28/82 (34%)
		FN3	339..431	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810