DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ama and Negr1

DIOPT Version :9

Sequence 1:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:329 Identity:96/329 - (29%)
Similarity:151/329 - (45%) Gaps:34/329 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LLIGLIFCLAI--SLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTN 76
            :|:.|..||..  |:|...:|      ..:::...||:....|.:|: |....:|..|      :
Mouse    18 VLLSLCSCLPAGQSVDFPWAA------VDNMLVRKGDTAVLRCYLED-GASKGAWLNR------S 69

  Fly    77 SVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSL 141
            |::.:..:..|: |.|.:::.     .....|:.:|||::|:|.|||.|.|....|.: |.::.|
Mouse    70 SIIFAGGDKWSV-DPRVSIST-----LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPR-TMQVHL 127

  Fly   142 QIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSV 206
            .::.||.|.:.:...| :.||.|:.|||.|.|.|:|.|||..    :.|:.........|.|..:
Mouse   128 TVQVPPKIYDISNDMT-INEGTNVTLTCLATGKPEPVISWRH----ISPSAKPFENGQYLDIYGI 187

  Fly   207 HRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMV-SHSAELECSVQGYPAPTVV 270
            .|...|.|.|.|:|....||.:.:||.|.|.|  .:|..|...:. ..|..:.|...|.|.|...
Mouse   188 TRDQAGEYECSAENDVSFPDVKKVRVIVNFAP--TIQEIKSGTVTPGRSGLIRCEGAGVPPPAFE 250

  Fly   271 WHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVI 335
            |:|....|.:.:...:....|    |.|:|.:.:|.:|.||:|.|.|.||||..:|.|.|.|.:.
Mouse   251 WYKGEKRLFNGQQGIIIQNFS----TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIE 311

  Fly   336 PVPS 339
            |..|
Mouse   312 PTTS 315

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AmaNP_731114.2 I-set 33..143 CDD:254352 25/109 (23%)
Ig 37..127 CDD:299845 21/89 (24%)
IG_like 154..234 CDD:214653 27/79 (34%)
IGc2 161..223 CDD:197706 22/61 (36%)
I-set 254..330 CDD:254352 25/75 (33%)
IGc2 254..322 CDD:197706 21/67 (31%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 3/22 (14%)
Ig strand A' 40..46 CDD:409353 0/5 (0%)
IG_like 41..129 CDD:214653 25/101 (25%)
Ig strand B 48..56 CDD:409353 2/7 (29%)
CDR1 56..60 CDD:409353 1/4 (25%)
FR2 61..68 CDD:409353 1/6 (17%)
Ig strand C 61..67 CDD:409353 1/5 (20%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 13/40 (33%)
Ig strand D 84..91 CDD:409353 1/11 (9%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 4/7 (57%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 2/9 (22%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 1/5 (20%)
IGc2 146..204 CDD:197706 22/61 (36%)
Ig strand B 150..157 CDD:409353 3/6 (50%)
Ig strand C 163..168 CDD:409353 3/4 (75%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 22/81 (27%)
putative Ig strand A 219..225 CDD:409353 2/7 (29%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833586
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR42757
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
76.840

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