DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and DIP-kappa

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	91/323 - (28%)
Similarity:	146/323 - (45%)	Gaps:	37/323 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTV 97
            |..::...:|..|||......|.||.:....|:|.:    .||.:::....|::| .:.|.::|.
  Fly    74 PRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVR----VDTQTILSIHHNVIS-QNSRISLTY 133

  Fly    98 TEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAEN-TPKSTLVTE 161
            .:     ...:...|:.:|.:|.|.|.||  |:.....::|..||:..||:|.|. |....:|.|
  Fly   134 ND-----HRSWYLHIKEVEETDRGWYMCQ--VNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVRE 191

  Fly   162 GQNLELTCHANGFPKPTISWAREHNAVMPAGG---HLLAEPTLRIRSVHRMDRGGYYCIAQNGEG 223
            |||:.|.|.|.|:|:|.:.|.||....|..||   :::....|.|..|.|:....|.|:|.||..
  Fly   192 GQNISLVCKARGYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVP 256

  Fly   224 QPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVAN 288
            ....:.:.:.|:|.|.:::........:.....|||..:.|||....|       .:.|...:.:
  Fly   257 PSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYW-------TTERGDMIIS 314

  Fly   289 TASSSG----TTTSV--------LRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIPVPS 339
            ..|.:|    ||::|        |:|.:||..|||.|.|.|.|.||..|..:.|.:  :|.|:
  Fly   315 DTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDE--MPTPT 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	26/109 (24%)
		Ig	37..127	CDD:299845	21/89 (24%)
		IG_like	154..234	CDD:214653	26/82 (32%)
		IGc2	161..223	CDD:197706	25/64 (39%)
		I-set	254..330	CDD:254352	27/87 (31%)
		IGc2	254..322	CDD:197706	24/79 (30%)
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	25/103 (24%)
		IG_like	82..174	CDD:214653	26/103 (25%)
		IG_like	184..267	CDD:214653	26/82 (32%)
		IGc2	191..255	CDD:197706	24/63 (38%)
		IG_like	282..368	CDD:214653	27/92 (29%)
		Ig	288..367	CDD:143165	27/85 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
	7	6.780